Protein Details: Glycine receptor subunit alpha-3

Protein ID

ICDB_Pro_0260

Protein Name

Glycine receptor subunit alpha-3

Gene Name

GLRA3

Organism

Homo sapiens (Human)

Length

464 amino acids

AlphaFoldDB

AF-O75311-F1-model_v4.pdb

Function

Sequence

MAHVRHFRTLVSGFYFWEAALLLSLVATKETDSARSRSAPMSPSDFLDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDMDDEVRESRFSFTAYGMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHEDIHQQQD

PDB Structures

5CFB 5TIN 5TIO 5VDH 5VDI

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

225;227;235-240;248;294

Disease

Cerebellar Ataxia;Cayman Type and Autosomal Recessive Cerebellar Ataxia

Location

Widely distributed throughout the central nervous system.